KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DSTYK
All Species:
22.42
Human Site:
S490
Identified Species:
44.85
UniProt:
Q6XUX3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6XUX3
NP_056190.1
929
105259
S490
S
V
D
Y
L
R
E
S
F
V
G
T
L
E
R
Chimpanzee
Pan troglodytes
Q4VSN5
930
105286
S491
S
V
D
Y
L
R
E
S
F
V
G
T
L
E
R
Rhesus Macaque
Macaca mulatta
Q20CR4
907
103188
S468
S
V
D
Y
L
R
E
S
F
V
G
T
L
E
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q6XUX1
927
104882
S488
S
V
D
Y
L
R
E
S
F
V
G
T
L
E
R
Rat
Rattus norvegicus
Q6XUX2
927
104879
S488
S
V
D
Y
L
R
E
S
F
V
G
T
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507776
635
71008
I265
A
N
M
E
F
K
D
I
I
I
P
E
N
G
E
Chicken
Gallus gallus
Q6XUX0
930
105391
E491
R
C
L
K
S
L
E
E
S
W
E
V
S
V
H
Frog
Xenopus laevis
Q67E01
916
104146
F479
V
D
Y
L
R
E
S
F
V
G
T
M
E
R
C
Zebra Danio
Brachydanio rerio
Q4VSN1
885
99530
V452
D
Y
L
R
E
S
F
V
G
T
L
E
R
C
L
Tiger Blowfish
Takifugu rubipres
Q4VSN2
921
103826
V483
D
Y
L
R
E
S
F
V
G
T
L
E
R
C
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Q1L6Q1
969
110409
I470
N
C
L
R
E
S
F
I
G
T
L
Q
R
C
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
A2CI35
953
108361
S502
S
V
E
L
L
R
E
S
F
L
G
T
L
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.3
N.A.
N.A.
91.2
90.9
N.A.
52.9
78.3
71.5
67.2
67.9
N.A.
37.9
N.A.
42.2
Protein Similarity:
100
99.6
96.6
N.A.
N.A.
94.4
93.9
N.A.
57.9
87.5
82.4
79.3
80.9
N.A.
54.2
N.A.
58.7
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
0
6.6
0
0
0
N.A.
0
N.A.
73.3
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
26.6
6.6
0
0
0
N.A.
6.6
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
17
0
0
0
0
0
0
0
0
0
0
0
25
9
% C
% Asp:
17
9
42
0
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
9
25
9
59
9
0
0
9
25
9
42
9
% E
% Phe:
0
0
0
0
9
0
25
9
50
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
25
9
50
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
0
17
9
9
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
34
17
50
9
0
0
0
9
25
0
50
0
25
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
9
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% Q
% Arg:
9
0
0
25
9
50
0
0
0
0
0
0
25
9
50
% R
% Ser:
50
0
0
0
9
25
9
50
9
0
0
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
25
9
50
0
0
0
% T
% Val:
9
50
0
0
0
0
0
17
9
42
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
17
9
42
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _